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Table 1 Demographic information, laboratory indicators, and neuropsychological tests of all subjects

From: Regional brain function study in patients with primary Sjögren’s syndrome

Characteristics

pSS (N = 68)

HCs (N = 69)

χ2/Z value

P value

Age (years)

50.22 ± 13.42

54.00 (46.00, 59.00)

-0.612φ

0.541

Sex (Male/Female)

1/67

1/68

0.000#

0.992

Education (years)

9.00 (6.00, 14.25)

9.00 (6.00, 12.00)

-1.019φ

0.308

Head motion

0.05 (0.04, 0.09)

0.06 (0.05, 0.09)

-0.263φ

0.793

Disease duration (months)

12.00 (0.00, 48.00)

/

/

/

Treatments (yes/no)

47/21

/

/

/

ESSDAI (scores)

2.00 (1.00, 5.00)

/

/

/

MMSE (scores)

29.00 (28.00, 30.00)

29.00 (28.00, 30.00)

-0.581φ

0.561

SAS (scores)

31.38 ± 5.45

26.00 (24.00, 30.00)

-4.736φ

< 0.001*

SDS (scores)

27.00 (22.25, 31.00)

27.00 (23.00, 30.00)

-0.060φ

0.952

NCT-A (seconds)

47.00 (38.25, 64.50)

47.35 ± 11.97

-0.532φ

0.595

DST (scores)

37.50 (21.25, 55.00)

34.36 ± 11.51

-1.208φ

0.227

IgG (g/L)

19.60 (15.15, 22.18)

/

/

/

IgA (g/L)

3.11 ± 1.50

/

/

/

IgM (g/L)

1.36 (0.94, 1.82)

/

/

/

C3 (g/L)

0.81 ± 0.03

/

/

/

C4 (g/L)

0.19 ± 0.00

/

/

/

anti-La/SS-B (negative/ positive)

44/24

/

/

/

anti-Ro/SS-A (negative/ positive)

8/60

/

/

/

  1. Note: pSS, primary Sjögren’s syndrome; HCs, healthy controls; ESSDAI, EULAR Sjögren’s Syndrome Disease Activity Index; MMSE, Mini-Mental State Examination; SAS, Self-Rating Anxiety Scale; SDS, Self-rating Depression Scale; NCT-A, Number Connection Test-Type A; DST, Digit Symbol Test; # indicates χ2 test; φ indicates Wilcoxon rank sum test; * indicates a significant level of P < 0.05