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Table 1 Demographic and clinical characteristics of IgAV patients, IgAVN, sl-IgAV and HC included in RNA sequencing

From: Exhausted natural killer cells in adult IgA vasculitis

Characteristics

IgAV (n = 6)

IgAVN (n = 3)

sl-IgAV (n = 3)

HC (n = 3)

Age*

66.5 (56.6–76.7)

66.6 (66.3–74.2)

64.0 (34.2–84.2)

53.0 (48.0–57.5)

Sex

1 M, 5 F

3 F

1 M, 2 F

3 F

BMI*

30.4 (24.6–35.9)

31.8 (26.0–40.0)

29.1 (20.4–34.5)

/

Symptom duration (day)*

5.5 (3.5–38)

5 (2–14)

6 (4–110)

/

Skin purpura

6

3

3

/

Daily proteinuria (g/day)*

0.351 (0.069–0.793)

0.474 (0.076–1.09)

0.228 (0.048–0.693)

/

Hematuria

3 microhematuria

3 microhematuria

0

/

CRP (g/l)*

51.5 (27.8–135.8)

58 (32–198)

45 (15–115)

/

SAA (µg/ml)

38.4 (0–175)

302 (92.5–933)

38.4 (0.00–598.0)

/

Number of lymphocytes (109/l)*

1.83 (1.08–2.62)

1.58 (0.75–2.57)

2.08 (1.19–2.76)

/

Number of neutrophils (109/l)*

5.12 (4.12–6.19)

4.5 (4.47–6.94)

7.46 (4.31–10.44)

/

BVAS*

7 (2–11)

8 (8–20)

2 (2–6)

/

Concurrent infection

1

0

1

/

Prior infection

2

1

1

/

  1. IgAV, immunoglobulin A vasculitis; IgAVN, IgAV with renal involvement, sl-IgAV, skin-limited IgAV; HC, healthy controls; M, male; F, female; BMI, body mass index; CRP, C-reactive protein; SAA, serum amyloid A; BVAS, Birmingham vasculitis activity score; * median (IQR)