Table 4 Lymphodepletion regimen in adolescents
From: CAR-T cell therapy for juvenile-onset autoimmune diseases: a promising future?
Regimen for lymphodepletion | |
|---|---|
Patient 1 (with severe renal insufficiency) Krickau and al. [22] | Fludarabine 12.5 mg/m2/d over 3 days cyclophosphamide 500 mg/m2 once |
Patient 2 Marasco and al. [23] | Fludarabine 90 mg/m2 (the duration of treatment was not reported) Cyclophosphamide 1500 mg/m2 (the duration of treatment was not reported) |
Patient 3 Nicolai and al. [24] | Fludarabine 90 mg/m2 over 3 days Cyclophosphamide 1000 mg/m2 over 2 days |