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Table 3 Incidence of development of RA, OA, and OA with joint replacement after truncal vagotomy versus superselective vagotomy

From: Vagotomy and the incidence of rheumatoid arthritis and osteoarthritis: a Danish register-based study

 

Truncal Vagotomy Cohort

(n = 2260)

Superselective Vagotomy Cohort

(n = 3810)

Incident RA, n* (%)

10 (0.7)

10 (0.3)

IR (95% CI) for RA

10.2 (6.5–15.3)

12.1 (8.8–16.1)

Crude HR (95% CI) for RA

3.68 (1.54–8.78)

1.0

Adjusted HR (95% CI)* for RA

3.08 (1.22–7.79)

1.0

Incident OA, n* (%)

30 (1.3)

30 (0.8)

IR (95% CI) for OA

46.9 (38.4–56.7)

85.9 (76.8–95.7)

Crude HR (95% CI) for OA

2.16 (1.32–3.53)

1.0

Adjusted HR (95% CI)* for OA

1.12 (0.64–1.94)

1.0

Incident OA w/JR, n* (%)

10 (0.4)

10 (0.3)

IR (95% CI) for OA w/JR

25.7 (19.5–33.2)

50.4 (43.5–58.1)

Crude HR (95% CI) for OA w/JR

2.24 (0.84–5.97)

1.0

Adjusted HR (95% CI)* for OA w/JR

0.61 (0.19–1.90)

1.0

  1. RA = rheumatoid arthritis; OA = osteoarthritis; IR = incidence rate per 1,000 person-years; HR = hazard ratio; 95% CI = 95% confidence interval; JR = joint replacement. *Rounded to the nearest 10. **Adjusted for age, sex, and calendar year