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Table 2 Linear regression models (simplified) for DAS28 and its different components, with sex as explanatory variable (adjusted for age at treatment initiation, Charlson comorbidity index, BMI, and Sjögren’s syndrome)

From: Gender differences in clinical and prescribing characteristics of biologic and targeted synthetic drugs in naïve patients with rheumatoid arthritis: Data from BIOBADASER III registry

Disease activity

Sex coefficient (ref. male)

(95% CI)

p value

DAS28-ESR

0.36

(0.24; 0.47)

 < 0.001

DAS28-CRP

0.09

(−0.03; 0.20)

0.131

SJC

−0.01

(−0.42; 0.40)

0.953

TJC

0.68

(0.12; 1.24)

0.017

PGA-VAS

0.38

(0.16; 0.59)

0.001

ESR

5.22

(3.01; 7.43)

 < 0.001

CRP

−3.63

(−6.90; −0.37)

0.029

  1. Abbreviations: DAS disease activity score, BMI body mass index, CI confidence interval, TJC tender joint count, SJC swollen joint count, PGA-VAS patient global assessment visual analogue scale, ESR erythrocyte sedimentation rate, CRP C-reactive protein